Alpha Psi Omega is a national honorary dramatic fraternity.

Beta Beta Beta is a national honor society for students in biological sciences.

Beta Gamma Sigma is a national honor society dedicated to the principles and ideals essential to a worthy life as well as a commendable business career.

Eta Sigma Phi is a national honor fraternity recognizing ability in classical studies.

Financial Management Association National Honor Society serves to encourage and reward scholarship and accomplishment in financial management, financial institutions, and investments among undergraduate and graduate students, and to encourage interaction among business executives, faculty, and students of finance.

Mu Phi Epsilon is an international music fraternity.

Omicron Delta Kappa is a leadership society with chapters in major colleges and universities.

Order of Omega is a national leadeship society that recognizes student achievement in promoting inter-fraternal (Greek) activities.

Phi Alpha Theta is an international honor society in history.

Phi Beta Kappa is the nation's oldest academic honor society, installed at Millsaps in the spring of 1989. It recognizes and encourages excellence in the liberal arts. The Millsaps chapter, Alpha of Mississippi, elects members from the senior class on the basis of broad cultural interests, scholarly achievement, and good character.

Phi Eta Sigma is a national honorary society that recognizes outstanding academic achievement in freshmen.

Pi Delta Phi is a national French honor society.

Pi Mu Epsilon is a national mathematics honorary.

Sigma Delta Pi is the international Spanish honorary.

Sigma Tau Delta is the international English honorary, dedicated to conferring distinction upon students of the English language and literature in undergraduate, graduate, and professional studies. It is one of the largest members of the Association of College Honor Societies, with over 600 active chapters.